Haemodynamics-driven developmental pruning
WebThus, changes of blood flow drive vessel pruning via lateral migration of ECs, leading to the simplification of the vasculature and possibly efficient routing of blood flow in the developing brain. Citation: Chen Q, Jiang L, Li C, Hu D, Bu J-w, et al. (2012) Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish. PLoS Biol ... WebFinally, we show that pruning events can be predicted using a haemodynamics based mathematical model of the midbrain vasculature. These findings demonstrate the existence of brain vessel pruning during development and provide novel insights into the role of …
Haemodynamics-driven developmental pruning
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WebAug 14, 2012 · They revealed that the 'vessel pruning' that naturally takes place during development (whereby the vasculature develops its optimum, relatively simplified final form through the disappearance... WebMy current research focuses on theoretical and computational neuroscience, network dynamics, wave turbulence, applied dynamical systems, and applied stochastic processes and includes the development of theoretical and computational tools for their …
WebHaemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish Article Full-text available Aug 2012 Qi Chen Luan Jiang Chun Li [...] Jiulin du The brain blood vasculature consists... WebResearchGate
Webtitle = "Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish", abstract = "The brain blood vasculature consists of a highly ramified vessel network that is tailored to meet its physiological functions. How the brain vasculature is formed has long been fascinating biologists. WebAug 14, 2012 · More information: Chen Q, Jiang L, Li C, Hu D, Bu J-w, et al. (2012) Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish. PLoS Biol 10(8): e1001374.
WebMay 26, 2024 · In summary, we present a broad methodological overview ranging from image enhancement to segmentation with a mixed approach of experimental, simulated, and augmented datasets to assess and validate vascular segmentation using the zebrafish brain vasculature as an example. © 2024 The Authors. Current Protocols published by Wiley … crystal palace fanzineWebThis vessel pruning leads to a developmental reduction of vascular network complexity that may facilitate efficient routing of midbrain blood flow. We further revealed that changes of blood flow ... crystal palace documentary channel 4WebOct 21, 2024 · Blood–retinal barrier (BRB) breakdown is responsible for multiple ocular diseases, such as diabetic retinopathy, age-related macular degeneration, and retinal vascular occlusive diseases. Increased vascular permeability contributes to vasogenic edema and tissue damage, with consequent adverse effects on vision. marc chiricoWebAug 13, 2024 · This shift provides ‘division of labor’ among the neural cells and tissues. It allows taking over of the specific barrier and neural support functions. Tight junctions are present in BBB which... marc ching dallasWebMy current research focuses on theoretical and computational neuroscience, network dynamics, wave turbulence, applied dynamical systems, and applied stochastic processes and includes the development of theoretical and computational tools for their … crystal palace fc supportersWebApr 17, 2015 · We propose that developmental vessel regression involves four discrete steps: (1) selection of the regressing branch, (2) lumen stenosis, (3) endothelial cell retraction, and (4) resolution of the regressing vessel segment. marc chizalletWebAug 14, 2012 · Haemodynamics-driven developmental pruning of brain vasculature in zebrafish. ... that the developing vasculature in the zebrafish midbrain undergoes not only angiogenesis but also extensive vessel pruning, which is driven by changes in blood flow. This pruning process shapes the initial exuberant interconnected meshwork into a … marc chipot