WebOct 1, 2006 · The Major Lysosomal Membrane Proteins LAMP-1 and LAMP-2 Participate in Differentiation of C2C12 Myoblasts. H. Sakane, K. Akasaki Biology, Chemistry Biological & pharmaceutical bulletin 2024 TLDR Results demonstrate that both LAMP-1 and Lamping-2 are involved in C2C12 myotube formation and Lamp-2 may contribute dominantly to it. 6 … Webportion of LAMP1/2-labeled organelles do not contain detect-able lysosomal hydrolases. We next asked whether LAMP1 is a sensitive marker for assessing lysosomal defects in …
Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and …
WebAdditionally, LAMP-1/CD107a is a commonly used marker for natural killer (NK) cell degranulation (3). LAMP-1 and another lysosomal-associated membrane protein, LAMP-2, together make up about half of all lysosome membrane proteins (1). Additionally, LAMP-1 has a role in presenting carbohydrate ligands to selectins (2). ... Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band … See more Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the See more LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. … See more • Cluster of differentiation See more • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information available in the PDB for Human Lysosome-associated membrane glycoprotein 1 See more LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic cancers such as pancreatic cancer See more • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and … See more custom obd garage
Mobility of late endosomal and lysosomal markers on …
WebGet better batch-to-batch reproducibility with a recombinant antibody Anti-LAMP1 antibody [EPR4204] - Lysosome Marker (ab108597) Research … WebAug 18, 2024 · LAMP-1 is a major protein component of the lysosomal membrane and a lysosomal marker protein . In our result, red fluorescence derived from LAMP-1-RFP was recognized in the transfected cells ... Schematic representation of LAMP-1-RFP in the lysosomal membrane. (B) HT1080 cells expressing LAMP-1-RFP were established by … WebOct 10, 2013 · PGRN was colocalized with Lamp1, a lysosomal marker, and Lamp1-positive areas in GRN-deficient (KO) mice were significantly expanded compared with wild-type (WT) mice after TBI. Expression of all the lysosome-related genes examined in KO mice was significantly higher than that in WT mice. The number of activated microglia … custom object