WebApr 13, 2011 · Many topogenic signals are short peptides, such as the ER translocation signal, the ER retention signal, nuclear import and export signals, and mitochondrial … WebJan 10, 2014 · The Sec substrates have specific topogenic signals and are targeted to the membrane-embedded SecYEG translocon that is a polypeptide-conducting channel. The translocon also has not only the ability to accept new proteins but also a hydrophobic segment to fit into the lipid phase of the membrane. Ito and Mori discuss the various …
TranslocationofaPhycoerythrin SubunitacrossFive …
WebApr 1, 2000 · v ol. 64, 2000 topogenic signals in membrane proteins 17 precise distance constraint that allows glycosylation of acceptor sites only when the Asn residue is located a minimum of 12 WebThe topogenic signal is suggested to comprise a Ser-Lys-Leu (SKL)-containing sequence located at the extreme carboxyl terminus (for a review, see Osumi and F’ujiki (1990)). In a yeast system such as Candida tropi- calk, however, the signal for AOX (PXP4) appears to be different (Small et al., 1988). coach gift set for him
Topogenesis of membrane proteins: determinants and dynamics
WebFour types of topogenic sequences could be distinguished: signal sequences, stop-transfer sequences, sorting sequences, and insertion sequences. Signal sequences initiate … WebMay 5, 1997 · The topogenic role of the hydrophobic signal domain was studied in vivo by expressing mutants of the asialoglycoprotein receptor subunit H1 in COS-7 cells. By replacing the 19-residue transmembrane segment of wild-type and mutant H1 by stretches of 7–25 leucine residues, we found that the length and hydrophobicity of the apolar … WebHowever, T. cruzi gGAPDH lacks one of the positively charged 'hotspot' motifs which have been proposed as topogenic signals for import into the glycosome, a unique microbody-like organelle. calendar for february 1977